Detection help in the fight against Hepatitis untreated

Monday, November 2, 2009

Are able to hepatitis patients from now on to get rid of this disease without being subjected to any chemotherapy, with the discovery of a type of genetic mutation, which gives the individual the ability to get rid of inflammation, where the experts felt that people with hepatitis epidemics have become dangerous to have the ability to overcome the infection and get rid of the virus without treatment.

It appeared from the results of a study conducted by researchers that people with hepatitis, have transformed SNP genetic material, and are more responsive to the treatment of hepatitis, which may save some patients from the virus.

The collaborative study conducted by researchers from Johns Hopkins University for the U.S. found type of genetic mutation, which gives the individual the ability to get rid of hepatitis C, without undergoing any treatment.

Experts believe that in a time when some people with hepatitis throughout their lives, and injured liver disease hazardous, which include cancer, there is another team unable to overcome the infection and get rid of the virus without treatment.

Says Dr. David Thomas, the research team to study: "If we knew the reasons some people get rid of the disease on their own, then we will be able to discover new ways to help other people who are not able to do so, or may even help prevent infection completely," .

In a previous study, the researchers found a shift in one of the chemicals to DNA DNA, a material known as a shortcut to SNP, near the gene, known as IL28B, which is believed to help in the immune response to infection by viral hepatitis.

It appeared from the results that people with hepatitis, and holding shift SNP genetic material, are more responsive to the treatment of hepatitis, which may save some patients from the virus.

In order to ascertain the effectiveness of newly discovered genetic mutation, the researchers collected information from six different studies and has already amassed over the years, DNA samples and information on hepatitis from people from around the world.

The research team then analyzed the DNA and IL28B gene from a total of 1008 patients, including 620 people on a sustainable basis and 388 were among the injured, but they no longer had any virus.

The analysis revealed that conducted the DNA, that 264 people among the 388 who have become their bodies free of any viruses, has happened to them genetic mutations in the subject of SNP. Here, re-Thomas says: "This is the strongest evidence has been reached so far to understand what would constitute a successful immune response.

To date, we do not know the importance of this shift, but what we do know is we need to do more research for the detection means and whether it will help prevent infection. "

While Dr. Theo said Associate Professor: "We are now considering whether the SNP turning this will give us an explanation also for some genetic basis for differences between persons with respect to the issue of recovery from viral infection."